RFID’s Expanding Role in Oncology Medication Management: A New Era of Precision, Safety, and Efficiency

Published: September 3, 2025

Cancer care continues to advance at a remarkable pace, with new drug development, increasingly complex scheduling, tighter margins for error, and growing pressure to deliver personalized, safe, and timely treatment. \

For oncology pharmacies, whether embedded within academic medical centers, outpatient infusion clinics, or hub-and-spoke health systems, these pressures are acutely felt in medication management.

High-cost injectables. Strict stability requirements. Medication shortages. These realities demand a level of inventory oversight and operational precision that manual systems simply cannot deliver. That’s where RFID technology is beginning to play a transformational role.

The Unique Demands of Oncology Medication Management

Few areas of healthcare place as much strain on inventory systems as oncology. Medications are often temperature and time-sensitive, prepared in sterile environments, and administered on-demand based on rapidly evolving treatment regimens. Delays, miscounts, or expired products don’t just pose operational headaches, they impact patient safety and outcomes as well as health system revenue and operations.

Yet despite the high stakes, many oncology settings still rely on manual spreadsheets, static databases, or disparate systems that lack real-time visibility. This creates blind spots in inventory tracking, slows down clinical decision-making during shortages, and contributes to waste when expensive medications expire unused in one site while needed at another. RFID-based inventory management presents an opportunity to close these gaps and elevate oncology pharmacy operations to a new standard of care.

RFID’s Proactive Approach in Oncology

RFID technology enables real-time visibility into medication location, movement, and status— eliminating blind spots and enabling decisive, forward-thinking actions. In oncology, this translates into several tangible benefits:

  • Track High-Cost Drug Inventory Instantly: When shortages strike or allocations are in place, being able to instantly locate every vial of a specific oncology agent, across infusion suites, clean rooms, and satellite pharmacies, empowers pharmacists and purchasers to act decisively and responsibly.
  • Expiration-Driven Redistribution: Oncology drugs often have short beyond-use-dates once compounded or removed from refrigeration. RFID-tagged inventory can be monitored across sites, allowing pharmacy leaders to proactively shift drugs nearing expiration to higher-use locations, reducing waste.
  • Sterile Area Workflow Optimization: Cleanrooms are critical but resource-intensive. RFID systems allow remote inventory checks without the need to don PPE or interrupt compounding workflows, freeing up valuable time and reducing exposure risk.
  • Enhanced Recall and Diversion Management: Oncology medications are not only expensive, they’re also at risk of diversion. RFID technology provides a digital chain of custody, making it faster to identify and isolate affected inventory or detect anomalies.
  • Infusion Center Readiness and Patient Flow: One of the greatest patient experience pain points in oncology is treatment delay. RFID tracking helps ensure that infusion centers are adequately stocked and can prepare therapies efficiently, minimizing wait times and stress for patients already navigating a difficult journey.

Supporting Health System Integration and Growth

As more oncology services shift to outpatient and ambulatory care settings, the need for a coordinated inventory strategy becomes paramount. Central pharmacies are often tasked with overseeing medication supply across dozens of locations, many of which operate on different schedules, formularies, and care models.

RFID-enabled systems serve as connective tissue in these decentralized environments. With a single platform providing inventory transparency across all points of care, health systems can support:

  • Therapeutic interchange and accurate forecasting during shortages
  • Optimized reallocation through real-time inventory visibility across locations
  • Financial stewardship through better inventory turns and reduced emergency orders
  • Regulatory compliance and audit readiness through detailed usage logs

The Future of Medication Management in Oncology Pharmacy

The momentum toward RFID adoption in oncology pharmacy reflects a broader shift in mindset: from reactive inventory management to proactive, data-driven oversight. Oncology teams are no longer satisfied with knowing what they ordered, they want to know what they have, where it is, when it expires, and how fast it’s moving.

According to recent industry reports, while RFID adoption in hospital pharmacies still hovers around 30%, that number is climbing, driven in part by specialty areas like oncology where the ROI is highest and the stakes are greatest. As more organizations transition from legacy systems to integrated digital solutions, the oncology space stands to benefit the most.

RFID in oncology is not just about tracking drugs, it’s about improving care. By reducing uncertainty, enhancing safety, and freeing up clinical staff to focus on patients rather than logistics, RFID helps oncology teams rise to the complexity of modern cancer care.

The future of oncology pharmacy will demand both clinical and operational excellence. As we move toward more personalized, distributed, and data-rich models of care, technologies like RFID will be foundational in supporting pharmacists as stewards of safety, efficiency, and innovation.

About the Author: Sean Gilman

Sean Gilman, PharmD, DPLA, BCCCP, is a pharmacy technology and operations leader with a background in critical care and health system pharmacy operations. As a former inpatient pharmacy operations manager, he brings frontline experience in regulatory compliance, medication safety, inventory optimization and automation. Sean currently serves as a Director of Clinical Strategy at Bluesight, where he works with health systems to improve inventory visibility, reduce medication waste, and implement RFID-driven solutions.